Plasma vs. serum

Differences between Serum and Plasma 4.4/5 (456)

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Differences between Serum and Plasma

Plasma vs. serum

 

S.N.

Serum

Plasma

1

Serum is the undiluted, extracellular portion of blood after adequate coagulation is complete. Plasma is a clear, straw-colored watery portion of the blood in which several types of blood cells are suspended.

2

Serum is part of blood which lack clotting factor. Plasma is composed of serum and clotting factor.

3

Acquired after centrifuging of coagulated blood. Acquired after centrifuging blood with anti-coagulant.

4

Anticoagulant are not needed to separate the serum. Anticoagulant are required to get plasma.

5

Less volume in comparison to plasma.
[Plasma – Fibrinogen (Clotting factor)= Serum]
Consists 55% of total volume of blood.

6

Difficult to separate and is time consuming. Comparatively easier and less time consuming than serum.

7

Lack fibrinogen. Contain fibrinogen.

8

Consists 90% water with dissolved proteins, minerals, hormones and carbon dioxide. Consists ~92% water with Proteins, Salts, Lipids, Glucose.

9

Density of serum is 1.024g/ml. Density of plasma is 1.025g/ml.

10

Can be reserved at 2 to 6 degrees centigrade for many days and may be stored at a low temperature in the freezer for various months. Can be stored for even 10 years from the date it has been collected.

11

An important source of electrolytes. Plasma is the main medium for excretory product transportation.

12

Cells are usually attached together by clot formation. Cells are not attached together and suspended in plasma.

13

Most preferred part of blood used in checking blood groups and diagnosis of diseases. Transferred to the patients who are suffering from hemophilia, shocks, burns, and other clotting problems and also those who lack blood cell.

Differences between Serum and Plasma

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